RAF Typhoon jets have conducted a mission with France's air force in a coordinated attack targeting an hidden munitions depot in Syrian territory operated by the IS group, as stated by the UK Ministry of Defence.
The location, identified by intelligence, was assessed as housing weapons and explosive materials, the statement said, and was located in mountains just to the north of the historic site of Palmyra in the heart of Syria.
"Our fighter planes employed Paveway IV guided bombs to hit a series of approach shafts leading to the facility... preliminary assessments indicate the target was engaged successfully," the MoD said.
There was no evidence of any civilian impact in the strike late on Saturday and each participating jet made a safe return, the MoD added.
The Typhoon FGR4s were supported by a Voyager tanker plane.
Daesh - referred to as Daesh - imposed extremist governance over significant areas in both Syria and Iraq prior to its 2019 collapse.
"This action demonstrates our UK leadership, and resolve to work closely with our partners, to eradicate any resurgence of the terrorist group and their harmful and extremist ideologies in the Middle East," Britain's Defence Chief the Defence Secretary remarked.
British military aircraft have conducted overwatch operations over Syria to "prevent any attempted resurgence" of Islamic State after its military defeat at the climactic battle in Baghuz in 2019, the authorities noted.
"I extend gratitude to every member of the UK armed forces involved in this mission for their expertise and their courage," the Defence Secretary said. "They were part of a great many British troops deployed over the holidays. This operation, to remove dangerous terrorists who threaten our way of life, demonstrates how our armed forces are prepared to act, continuously, keeping Britain secure domestically and strong abroad."
Last December, the American forces conducted what it called a "massive strike" against IS targets in the country, following an attack killed two US troops and a civilian linguist in Palmyra.
The UN estimates Islamic State still maintains roughly 5-7 thousand combatants in Iraq and Syria.